WEBVTT 1 00:00:00.496 --> 00:00:03.670 Have you ever wondered why people can respond differently 2 00:00:03.750 --> 00:00:05.168 to the same medicine? 3 00:00:05.980 --> 00:00:09.270 Many factors affect how a medication works for you, 4 00:00:09.350 --> 00:00:13.450 including your age, gender, other medications or illnesses, 5 00:00:13.530 --> 00:00:16.688 your diet and exercise, and your overall health. 6 00:00:17.630 --> 00:00:20.544 Your response is also affected by your genetics. 7 00:00:21.370 --> 00:00:24.720 Pharmacogenetics can help determine how a medication 8 00:00:24.800 --> 00:00:26.000 can work for you. 9 00:00:26.810 --> 00:00:30.230 Your healthcare provider has recommended a genetic test 10 00:00:30.310 --> 00:00:32.352 called pharmacogenetic testing. 11 00:00:33.380 --> 00:00:37.740 This video will explain pharmacogenetics and provide information 12 00:00:37.820 --> 00:00:40.992 that can help you decide if testing is right for you. 13 00:00:41.990 --> 00:00:46.368 Your DNA has instructions for your body on how to grow and function. 14 00:00:47.060 --> 00:00:48.580 On the outside of your body, 15 00:00:48.660 --> 00:00:51.880 your DNA determine your basic physical features, 16 00:00:51.960 --> 00:00:53.904 like your eye color or your height. 17 00:00:54.800 --> 00:00:58.320 On the inside of your body, your DNA provide a blueprint 18 00:00:58.400 --> 00:01:01.830 for your tissues and organs, including the proteins 19 00:01:01.910 --> 00:01:04.896 that process the medications you take in your liver. 20 00:01:06.080 --> 00:01:09.472 Each person's body breaks down medications differently. 21 00:01:10.280 --> 00:01:12.300 Depending on your genetic makeup, 22 00:01:12.380 --> 00:01:16.752 you may have decreased or increased sensitivity to certain medications. 23 00:01:17.520 --> 00:01:20.528 Some people may break down medicines very slowly, 24 00:01:21.160 --> 00:01:24.352 others may break down the same medicines more quickly. 25 00:01:25.130 --> 00:01:28.020 Traditionally, when a new medicine is prescribed, 26 00:01:28.100 --> 00:01:29.984 a standard dose is used. 27 00:01:30.700 --> 00:01:33.424 This standard dose works well for most people. 28 00:01:34.210 --> 00:01:38.200 In other people, this same dose may cause unwanted side effects 29 00:01:38.280 --> 00:01:40.016 or not work as expected. 30 00:01:40.950 --> 00:01:44.000 Most of the time, your body processes medications 31 00:01:44.080 --> 00:01:47.536 at the usual rate and the standard dose works well. 32 00:01:48.590 --> 00:01:52.440 Pharmacogenetic testing can help your healthcare provider predict 33 00:01:52.520 --> 00:01:55.248 what your body's response to a medicine will be. 34 00:01:56.030 --> 00:01:59.120 For some medicines, pharmacogenetic test results 35 00:01:59.200 --> 00:02:04.220 can reveal if a higher or lower dose or a completely different medicine 36 00:02:04.300 --> 00:02:05.696 might work better for you. 37 00:02:06.640 --> 00:02:09.590 Depending on your current or expected medications, 38 00:02:09.670 --> 00:02:13.300 your healthcare provider will determine which pharmacogenetic tests 39 00:02:13.380 --> 00:02:15.568 are needed to guide your treatment. 40 00:02:16.580 --> 00:02:19.240 After your pharmacogenetic test is selected, 41 00:02:19.320 --> 00:02:21.152 you will provide a DNA sample. 42 00:02:21.990 --> 00:02:25.710 The test results will go into your electronic medical record 43 00:02:25.790 --> 00:02:29.010 and your health care providers, including pharmacists, 44 00:02:29.090 --> 00:02:32.620 will help you understand your results and what they might mean 45 00:02:32.700 --> 00:02:36.944 for drugs you are taking now or for medications you take in the future. 46 00:02:38.140 --> 00:02:41.680 If you have any questions before your pharmacogenetics appointment, 47 00:02:42.096 --> 00:02:43.392 please give us a call.