Clinician Resources

As part of the UF Clinical and Translational Science Institute, the UF Health Precision Medicine Program is working with clinicians at UF Health and at community-based health systems throughout Florida to implement pharmacogenetic testing within their patient care processes. The following resources are available for clinicians interested in learning more about implementing pharmacogenomics. If you are a clinician at UF Health or a community-based health system in Florida and would like to explore partnering with the UF Health Precision Medicine Program, please contact us at PMP-HELP@ctsi.ufl.edu.

UF Health Precision Medicine Program Resources

• UF Health Clinical Services & Patient Resources
• SNP•its, our online publication focused on the clinical implications of pharmacogenomics research findings
• Education

Other Resources

• PharmGKB, a comprehensive resource that curates knowledge about the impact of genetic variation on drug response for clinicians and researchers
• Clinical Pharmacogenetics Implementation Consortium
• Personalized Medicine Coalition
• The Genetic Information Nondiscrimination Act (GINA) – A Discussion Guide for Clinicians, a resource developed in collaboration with the National Coalition for Health Professional Education in Genetics

Publications on Pharmacogenomics Implementations

The publications below include recent descriptions of clinical pharmacogenomics implementations at UF Health and other early adopters, including Cleveland Clinic Center for Personalized Medicine, Coriell Institute for Medical Research, Mayo Clinic, St. Jude Children’s Research Hospital, University of Chicago, University of Maryland, University of North Carolina and Vanderbilt University.

Article	PubMed ID
Bielinksi SJ, Olson JE, Jyotishman P, et al. Preemptive genotyping for personalized medicine: design of the right drug, right dose, right time—using genomic data to individualize treatment protocol. May Clin Proc 2014;89:25-33.	24388019
Crews KR, Cross SJ, McCormick JN, et al. Development and implementation of a pharmacist-managed clinical pharmacogenetics service. Am J Health-Sys Pharm 2011;68:143-50.	21200062
Ferreri SP et al. Implementation of a pharmacogenomics service in a community pharmacy. J Am Pharm Assoc. 2014;54:172‐80.	24632932
Gharani N, Keller MA, Stack CB, et al. The Coriell personalized medicine collaborative pharmacogenomics appraisal, evidence scoring and interpretation system. Genome Med 2013;5:93.	24134832
Hoffman JM, et al. PG4KDS: A model for the clinical implementation of pre‐emptive pharmacogenetics. Am J Med Genet C Semin Med Genet. 2014;166:45‐55.	24619595
Lazaridis KN et al. Implementing individualized medicine into the medical practice. Am J Med Genet C Semin Med Genet. 2014;166(1):15‐23.	24616301
O’Donnell PH, et al. Adoption of a clinical pharmacogenomics implementation program during outpatient care‐initial results of the University of Chicago “1200 Patients Project.” Am J Med Genet C Semin Med Genet. 2014;166:68‐75.	24616296
Pulley JM, Denny JC, Peterson JF, et al. Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project 2012;92:87-95.	22588608
Shuldiner AR et al. Implementation of pharmacogenetics: The University of Maryland personalized anti‐platelet pharmacogenetics program. Am J Med Genet C Semin Med Genet. 2014;166:76‐84.	24616408
Teng K, et al. Cleveland Clinic’s Center for Personalized Healthcare: setting the stage for value-based care. Pharmacogenomics. 2014;15:587-591.	24798715
Van Driest S et al. Clinically actionable genotypes among 10,000 patients with preemptive pharmacogenomic testing. Clin Pharmacol Ther. 2014;95:423‐31.	24253661
Weitzel KW, et al. Clinical pharmacogenetics implementation: Approaches, successes, and challenges. Am J Med Genet C Semin Med Genet. 2014;166:56‐67.	24616371